Tronolane Anesthetic for Hemorrhoids

Generic Name: pramoxine and zinc oxide topical (pra MOX een and ZINK OX ide TOP ik al)

Brand Names: Anusol, Tronolane Anesthetic for Hemorrhoids, Tucks Hemorrhoidal

What is Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

Pramoxine is an anesthetic, or "numbing medicine." It works by interfering with pain signals sent from the nerves to the brain.

Zinc oxide is a mineral.

The combination of pramoxine and zinc oxide topical (for the skin) is used to treat itching, burning, irritation, or other rectal discomfort caused by hemorrhoids or painful bowel movements.

Pramoxine and zinc oxide topical may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

You should not use this medication if you are allergic to pramoxine, zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax. Avoid getting this medicine in your eyes, nose, or vagina. If this does happen, rinse with water. Pramoxine and zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing lesions around your rectum. Stop using pramoxine and zinc oxide topical and call your doctor if your symptoms do not improve after 7 day of treatment, or if your condition clears up and then comes back.

What should I discuss with my healthcare provider before using Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

You should not use this medication if you are allergic to pramoxine, zinc, dimethicone, lanolin, cod liver oil, petroleum jelly, parabens, mineral oil, or wax.

Ask a doctor or pharmacist if it is safe for you to use this medicine if you are allergic to any drugs or any other numbing medicines.

FDA pregnancy category C. It is not known whether pramoxine and zinc oxide topical will harm an unborn baby. Do not use this medication without medical advice if you are pregnant. It is not known whether pramoxine and zinc oxide topical passes into breast milk or if it could harm a nursing baby. Do not use this medication without medical advice if you are breast-feeding a baby.

How should I use Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended.

Wash your hands before and after applying this medicine. Wash the affected skin area with warm water and a mild soap. Rinse and dry the area thoroughly.

Pramoxine and zinc oxide topical may be used on the rectum after each bowel movement to treat hemorrhoid pain and itching.

Do not insert this medication into your rectum. Use pramoxine and zinc oxide topical only on the outside of the area.

Pramoxine and zinc oxide topical will not treat a bacterial or fungal infection. Call your doctor if you have any signs of infection such as redness and warmth or oozing lesions around your rectum. Stop using this medicine and call your doctor if your symptoms do not improve after 7 day of treatment, or if your condition clears up and then comes back. Store at room temperature away from moisture and heat. Keep the cap tightly closed when not in use.

What happens if I miss a dose?

Since pramoxine and zinc oxide topical is used on an as needed basis, you are not likely to miss a dose. Using extra cream or ointment to make up a missed dose will not make the medication more effective.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

Avoid getting this medicine in your eyes, nose, or vagina. If this does happen, rinse with water.

Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using pramoxine and zinc oxide topical and call your doctor at once if you have a serious side effect such as:

• 
  

  any new redness or swelling where the medicine was applied;

  
  


• 
  

  severe pain, burning, or stinging where the medicine is applied; or

  
  


• 
  

  rectal bleeding or continued pain.

  
  

Less serious side effects are more likely, and you may have none at all.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Tronolane Anesthetic for Hemorrhoids (pramoxine and zinc oxide topical)?

It is not likely that other drugs you take orally or inject will have an effect on topically applied pramoxine and zinc oxide. But many drugs can interact with each other. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start a new medication without telling your doctor.

More Tronolane Anesthetic for Hemorrhoids resources

• Tronolane Anesthetic for Hemorrhoids Side Effects (in more detail)
• Tronolane Anesthetic for Hemorrhoids Use in Pregnancy & Breastfeeding
• 0 Reviews for Tronolane Anesthetic for Hemorrhoids - Add your own review/rating

• Tucks Hemorrhoidal Ointment MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Tronolane Anesthetic for Hemorrhoids with other medications

• Hemorrhoids

Where can I get more information?

• Your pharmacist can provide more information about pramoxine and zinc oxide topical.

See also: Tronolane Anesthetic for Hemorrhoids side effects (in more detail)

thiothixene

Generic Name: thiothixene (THYE oh THIX een)

Brand Names: Navane

What is thiothixene?

Thiothixene is an antipsychotic medication. It affects the actions of chemicals in your brain.

Thiothixene is used to treat schizophrenia.

Thiothixene may also be used for purposes not listed in this medication guide.

What is the most important information I should know about thiothixene?

Thiothixene is not for use in psychotic conditions related to dementia. Thiothixene may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions.

You should not use this medication if you are allergic to thiothixene, or if you have a blood cell disorder such as anemia or low white blood cells or platelets, or if you have decreased alertness caused by taking certain medications or drinking alcohol.

Call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs.

Thiothixene may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Do not drink alcohol. Thiothixene can increase the effects of alcohol, which could be dangerous.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Thiothixene can decrease perspiration and you may be more prone to heat stroke.

What should I discuss with my healthcare provider before taking thiothixene?

Thiothixene is not for use in psychotic conditions related to dementia. Thiothixene may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not use thiothixene if you are allergic to it, or if you have:

• 
  

  a blood cell disorder such as anemia, low white blood cell counts, or low platelets; or

  
  


• 
  

  drowsiness, slow breathing, weak pulse, or decreased alertness caused by taking certain medications or drinking alcohol.

  
  

To make sure you can safely take thiothixene, tell your doctor if you have any of these other conditions:

• 
  

  epilepsy or other seizure disorder;

  
  


• 
  

  heart disease;

  
  


• 
  

  a history of low white blood cell (WBC) counts;

  
  


• 
  

  a history of breast cancer; or

  
  


• 
  

  if you are addicted to alcohol.

  
  

Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Taking antipsychotic medication during the last 3 months of pregnancy may cause problems in the newborn, such as withdrawal symptoms, breathing problems, feeding problems, fussiness, tremors, and limp or stiff muscles. However, you may have withdrawal symptoms or other problems if you stop taking your medicine during pregnancy. If you become pregnant while taking thiothixene, do not stop taking it without your doctor's advice. It is not known whether thiothixene passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Thiothixene should not be given to a child younger than 12 years old.

How should I take thiothixene?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results.

You may not start feeling better right away when you start taking thiothixene. For best results, keep using the medication as directed. Talk with your doctor if your symptoms do not improve during treatment.

You will need regular medical tests to be sure this medication is not causing harmful effects. Visit your doctor regularly.

Store at room temperature away from moisture and heat.

See also: Thiothixene dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include drowsiness, dizziness, muscle stiffness or twitching, increased salivation, trouble swallowing, weakness, loss of balance or coordination, and fainting.

What should I avoid while taking thiothixene?

Thiothixene may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.

Do not drink alcohol. Thiothixene can increase the effects of alcohol, which could be dangerous.

Avoid becoming overheated or dehydrated during exercise and in hot weather. Thiothixene can decrease perspiration and you may be more prone to heat stroke.

Avoid exposure to sunlight or tanning beds. Thiothixene can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Thiothixene side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop taking thiothixene and call your doctor at once if you have a serious side effect such as:

• 
  

  very stiff (rigid) muscles, high fever, sweating, confusion, fast or uneven heartbeats, feeling like you might pass out;

  
  


• 
  

  twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs;

  
  


• 
  

  tremor (uncontrolled shaking);

  
  


• 
  

  trouble swallowing;

  
  


• 
  

  vision changes;

  
  


• 
  

  swelling in your hands or feet;

  
  


• 
  

  seizure (convulsions);

  
  


• 
  

  pale skin, easy bruising or bleeding, unusual weakness; or

  
  


• 
  

  fever, chills, body aches, flu symptoms.

  
  

Less serious side effects may include:

• 
  

  dizziness or drowsiness;

  
  


• 
  

  feeling restless or agitated;

  
  


• 
  

  sleep problems (insomnia);

  
  


• 
  

  breast swelling or discharge;

  
  


• 
  

  changes in your menstrual periods;

  
  


• 
  

  nausea, vomiting, diarrhea, constipation;

  
  


• 
  

  changes in weight or appetite;

  
  


• 
  

  dry mouth, increased thirst; or

  
  


• 
  

  impotence, loss of interest in sex.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Thiothixene Dosing Information

Usual Adult Dose for Psychosis:

Oral: Initial dose (mild conditions): 2 to 3 mg orally 3 times a day.
Maintenance dose: May increase up to 15 mg/day.
Initial dose (severe conditions): 5 mg orally twice a day.
Maintenance dose: 20 to 30 mg/day.
Maximum dose: 60 mg/day.

Usual Pediatric Dose for Psychosis:

12 years of age or older:
Initial dose (mild conditions): 2 to 3 mg orally 3 times a day.
Maintenance dose: May increase up to 15 mg/day.
Initial dose (severe conditions): 5 mg orally twice a day.
Maintenance dose: 20 to 30 mg/day.
Maximum dose: 60 mg/day.

Less than 12 years:
Dose not well established (use not recommended): 0.25 mg/kg/day in divided doses

What other drugs will affect thiothixene?

Before using thiothixene, tell your doctor if you regularly use other medicines that make you sleepy (such as cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). You should not take thiothixene if you have drowsiness caused by other medications.

Tell your doctor about all other medications you use, especially:

• 
  

  carbamazepine (Carbatrol, Tegretol);

  
  


• 
  

  blood pressure medications;

  
  


• 
  

  atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  
  


• 
  

  bronchodilators such as ipratroprium (Atrovent) or tiotropium (Spiriva);

  
  


• 
  

  glycopyrrolate (Robinul);

  
  


• 
  

  mepenzolate (Cantil);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare); or

  
  


• 
  

  irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

  
  

This list is not complete and other drugs may interact with thiothixene. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More thiothixene resources

• Thiothixene Side Effects (in more detail)
• Thiothixene Dosage
• Thiothixene Use in Pregnancy & Breastfeeding
• Drug Images
• Thiothixene Drug Interactions
• Thiothixene Support Group
• 3 Reviews for Thiothixene - Add your own review/rating

• thiothixene Advanced Consumer (Micromedex) - Includes Dosage Information


• Thiothixene Prescribing Information (FDA)


• Thiothixene Professional Patient Advice (Wolters Kluwer)


• Thiothixene Monograph (AHFS DI)


• Thiothixene MedFacts Consumer Leaflet (Wolters Kluwer)


• Navane Advanced Consumer (Micromedex) - Includes Dosage Information


• Navane Prescribing Information (FDA)

Compare thiothixene with other medications

• Psychosis

Where can I get more information?

• Your pharmacist can provide more information about thiothixene.

See also: thiothixene side effects (in more detail)

Tri-Vit with Fluoride and Iron Drops

Dosage Form: oral solution
TRI-VIT WITH FLUORIDE 0.25 mg AND IRON DROPS


Rx only

Supplement Facts
Dosage Size 1 mL (Mark on Dropper)
Amount Per	% Daily Value
1 mL	Infants	Children Under
		Age 4 Years
Vitamin A 1500 IU	100%	60%
Vitamin C 35 mg	100%	88%
Vitamin D 400 IU	100%	100%
Iron 10 mg	67%	100%
Fluoride 0.25 mg	*	*
*Daily Value (DV) not established

Active ingredient for caries prophylaxis:

Each 1 mL contains 0.25 mg fluoride as sodium fluoride.

Other ingredients:

ascorbic acid (Vitamin C), caramel color, cholecalciferol (Vitamin D3), ferrous sulfate, flavor, glycerin, polysorbate 80, purified water, vitamin A palmitate

CLINICAL PHARMACOLOGY:

It is well established that fluoridation of the water supply (1 ppm fluoride) during the period of tooth development leads to a significant decrease in the incidence of dental caries. Hydroxyapatite is the principal crystal for all calcified tissue in the human body. The fluoride ion reacts with the hydroxyapatite in the tooth as it is formed to produce the more caries-resistant crystal, fluorapatite. Three stages of fluoride deposition in tooth enamel can be distinguished:1 1) Small amounts (reflecting the low levels of fluoride in tissue fluids) are incorporated into the enamel crystals while they are being formed. 2) After enamel has been laid down, fluoride deposition continues in the surface enamel. Diffusion of fluoride from the surface inward is apparently restricted. 3) After eruption, the surface enamel acquires fluoride from water, food, supplementary fluoride, and smaller amounts from saliva.

INDICATIONS AND USAGE:

Supplementation of the diet with vitamins A, D, C, and iron. Supplementation of the diet with fluoride for caries prophylaxsis. TRI-VIT with FLUORIDE 0.25 mg and IRON (vitamins A, D, C, iron and fluoride) drops provide fluoride in drop form for infants and young children from 6 months to 3 years of age in areas where the drinking water contains less than 0.3 ppm of fluoride and for children ages 3 to 6 years in areas where the drinking water contains 0.3 through 0.6 ppm of fluoride.2,3

WARNING: Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. Keep this product out of the reach of children. In case of accidental overdose, call a doctor or poison control center immediately.

PRECAUTIONS:

The suggested dose should not be exceeded since dental fluorosis may result from continued ingestion of large amounts of fluoride. When prescribing TRI-VIT with FLUORIDE 0.25 mg and IRON drops: 1) Determine the fluoride content of the drinking water from all major sources. 2) Make sure the child is not receiving significant amounts of fluoride from other sources such as medications and swallowed toothpaste. 3) Periodically check to make sure that the child does not develop significant dental fluorosis.

TRI-VIT with FLUORIDE 0.25 mg and IRON drops should be dispensed in the original plastic container, since contact with glass leads to instability and precipitation. (The amount of sodium fluoride in the 50-mL size is well below the maximum to be dispensed at one time according to recommendations of the American Dental Association.)

ADVERSE REACTIONS:

Allergic rash and other idiosyncrasies have been rarely reported.

DOSAGE AND ADMINISTRATION:

1 mL daily, or as prescribed. May be dropped directly into mouth with dropper, or mixed with fruit juice, cereal or other food. USE FULL DOSAGE

DISPENSE in original container

Occasional deepening of color has no significant effect on vitamin potency.

While taking drops with iron, a slight darkening of the teeth may occur. Brushing will minimize this temporary condition.

After opening, store away from direct light.

Your doctor or dentist is the best source of counsel and guidance in your child’s fluoride supplementation.

REFERENCES

1. Brudevold F, McCann HG. Fluoride and caries control - Mechanism of action. In: Nizel AE, ed. The Science of Nutrition and Its Application in Clinical Dentistry. Philadelphia: WB Saunders Co.; 1966;331-347.


2. American Academy of Pediatrics, Committee on Nutrition: Fluoride Supplementation for Children: Interim Policy Recommendations. Pediatrics. 1995;95:777.


3. American Dental Association Council on Dental Therapeutics. New Fluoride Schedule Adopted. ADA News. May 16, 1994;12-14.

Manufactured for:

QUALITEST PHARMACEUTICALS

130 VINTAGE DRIVE

HUNTSVILLE, AL 35811

R4/09-R5

8277542

PRINCIPAL DISPLAY PANEL

 

PRINCIPAL DISPLAY PANEL

 

Tri-Vit with Fluoride and Iron Drops  vitamin a palmitate and ascorbic acid and cholecalciferol and ferrous sulfate and sodium fluoride solution  solution

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0603-1787 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength VITAMIN A PALMITATE (VITAMIN A) VITAMIN A PALMITATE 1500 [iU]  in 1 mL ASCORBIC ACID (ASCORBIC ACID) ASCORBIC ACID 35 mg  in 1 mL CHOLECALCIFEROL (CHOLECALCIFEROL) CHOLECALCIFEROL 400 [iU]  in 1 mL FERROUS SULFATE (IRON) FERROUS SULFATE 10 mg  in 1 mL SODIUM FLUORIDE (FLUORIDE ION) SODIUM FLUORIDE 0.25 mg  in 1 mL

Inactive Ingredients Ingredient Name Strength GLYCERIN   POLYSORBATE 80   WATER   ANHYDROUS CITRIC ACID   SODIUM HYDROXIDE

Product Characteristics Color BROWN (clear and brown) Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0603-1787-47 1 BOTTLE In 1 CARTON contains a BOTTLE, PLASTIC 1 50 mL In 1 BOTTLE, PLASTIC This package is contained within the CARTON (0603-1787-47)

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
UNAPPROVED DRUG OTHER		11/17/1997

Labeler - Qualitest Pharmaceuticals (011103059)

Establishment
Name	Address	ID/FEI	Operations
Vintage Pharmaceuticals-Huntsville		825839835	MANUFACTURE

Revised: 07/2011Qualitest Pharmaceuticals

Tylenol Childrens Plus Cough & Runny Nose

Generic Name: acetaminophen, chlorpheniramine, and dextromethorphan (a SEET a MIN oh fen, klor fen IR a meen, dex troe meth OR fan)

Brand Names: Coricidin HBP Maximum Strength Flu, Mapap Cough & Sinus Formula, Triaminic Flu Cough & Fever, Triaminic Multi-Symptom Fever, Tylenol Childrens Plus Cough & Runny Nose

What is Tylenol Childrens Plus Cough & Runny Nose (acetaminophen, chlorpheniramine, and dextromethorphan)?

Acetaminophen is a pain reliever and fever reducer.

Chlorpheniramine is an antihistamine that reduces the effects of the natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Dextromethorphan is a cough suppressant. It affects the cough reflex in the brain that triggers coughing.

The combination of acetaminophen, chlorpheniramine, and dextromethorphan is used to treat headache, fever, body aches, cough, runny nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

This medicine will not treat a cough that is caused by smoking, asthma, or emphysema.

Acetaminophen, chlorpheniramine, and dextromethorphan may also be used for purposes not listed in this medication guide.

What is the most important information I should know about this medicine?

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not take this medication without a doctor's advice if you have ever had alcoholic liver disease (cirrhosis) or if you drink more than 3 alcoholic beverages per day. You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen, and can increase certain side effects of chlorpheniramine. Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP.

What should I discuss with my healthcare provider before taking this medicine?

You should not use this medicine if you have severe constipation, a blockage in your stomach or intestines, or if you are unable to urinate. Do not use this medicine if you have untreated or uncontrolled diseases such as glaucoma, asthma or COPD, high blood pressure, heart disease, coronary artery disease, or overactive thyroid. Do not use this medicine if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have:

• 
  

  liver disease, cirrhosis, a history of alcoholism, or if you drink more than 3 alcoholic beverages per day;

  
  


• 
  

  a blockage in your digestive tract (stomach or intestines);

  
  


• 
  

  kidney disease;

  
  


• 
  

  cough with mucus, or cough caused by emphysema or chronic bronchitis;

  
  


• 
  

  enlarged prostate or urination problems; or

  
  


• 
  

  if you take potassium (Cytra, Epiklor, K-Lyte, K-Phos, Kaon, Klor-Con, Polycitra, Urocit-K).

  
  

It is not known whether acetaminophen, chlorpheniramine, and dextromethorphan will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant. Acetaminophen, chlorpheniramine, and dextromethorphan may pass into breast milk and may harm a nursing baby. Antihistamines may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Artificially sweetened cold medicine may contain phenylalanine. If you have phenylketonuria (PKU), check the medication label to see if the product contains phenylalanine.

How should I take this medicine?

Use exactly as directed on the label, or as prescribed by your doctor. Do not use in larger or smaller amounts or for longer than recommended. This medicine is usually taken only for a short time until your symptoms clear up.

Do not take more of this medication than is recommended. An overdose of acetaminophen can damage your liver or cause death. Do not give this medication to a child younger than 4 years old. Always ask a doctor before giving a cough or cold medicine to a child. Death can occur from the misuse of cough and cold medicines in very young children.

Measure liquid medicine with a special dose measuring spoon or medicine cup, not with a regular table spoon. If you do not have a dose measuring device, ask your pharmacist for one.

Do not take for longer than 7 days in a row. Stop taking the medicine and call your doctor if you still have a fever after 3 days of use, you still have pain after 7 days (or 5 days if treating a child), if your symptoms get worse, or if you have a skin rash, ongoing headache, or any redness or swelling.

If you need surgery or medical tests, tell the surgeon or doctor ahead of time if you have taken this medicine within the past few days. Store at room temperature away from moisture and heat. Do not allow liquid medicine to freeze.

What happens if I miss a dose?

Since this medicine is taken when needed, you may not be on a dosing schedule. If you are taking the medication regularly, take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of acetaminophen can be fatal.

The first signs of an acetaminophen overdose include loss of appetite, nausea, vomiting, stomach pain, sweating, and confusion or weakness. Later symptoms may include pain in your upper stomach, dark urine, and yellowing of your skin or the whites of your eyes.

Overdose symptoms may also include severe forms of some of the side effects listed in this medication guide.

What should I avoid while taking this medicine?

Ask a doctor or pharmacist before using any other cold, allergy, pain, or sleep medication. Acetaminophen (sometimes abbreviated as APAP) is contained in many combination medicines. Taking certain products together can cause you to get too much acetaminophen which can lead to a fatal overdose. Check the label to see if a medicine contains acetaminophen or APAP. Avoid drinking alcohol. It may increase your risk of liver damage while you are taking acetaminophen, and can increase certain side effects of chlorpheniramine. This medicine may cause blurred vision or impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly.

This medicine side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  chest pain, rapid pulse;

  
  


• 
  

  fast, slow, or uneven heart rate;

  
  


• 
  

  severe dizziness or anxiety, feeling like you might pass out;

  
  


• 
  

  severe headache;

  
  


• 
  

  mood changes, confusion, hallucinations, severe nervousness;

  
  


• 
  

  tremor, seizure (convulsions);

  
  


• 
  

  fever, easy bruising or bleeding, unusual weakness;

  
  


• 
  

  urinating less than usual or not at all;

  
  


• 
  

  nausea, pain in your upper stomach, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of your skin or eyes); or

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, chest pain, uneven heartbeats, seizure).

  
  

Less serious side effects may include:

• 
  

  dizziness, drowsiness, mild headache;

  
  


• 
  

  dry mouth, nose, or throat;

  
  


• 
  

  constipation, diarrhea, mild nausea, upset stomach;

  
  


• 
  

  blurred vision;

  
  


• 
  

  feeling restless or irritable; or

  
  


• 
  

  sleep problems (insomnia).

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect this medicine?

Ask a doctor or pharmacist before using this medicine if you regularly use other medicines that make you sleepy (such as narcotic pain medication, sedatives, sleeping pills, muscle relaxers, and medicine for seizures, depression or anxiety). They can add to sleepiness caused by chlorpheniramine.

Ask a doctor or pharmacist if it is safe for you to use acetaminophen, chlorpheniramine, and dextromethorphan if you are also using any of the following drugs:

• 
  

  leflunomide (Arava);

  
  


• 
  

  topiramate (Topamax);

  
  


• 
  

  zonisamide (Zonegran);

  
  


• 
  

  an antibiotic, antifungal medicine, sulfa drug, or tuberculosis medicine;

  
  


• 
  

  an antidepressant;

  
  


• 
  

  birth control pills or hormone replacement therapy;

  
  


• 
  

  bladder or urinary medications;

  
  


• 
  

  blood pressure medication;

  
  


• 
  

  a bronchodilator;

  
  


• 
  

  cancer medicine;

  
  


• 
  

  cholesterol-lowering medications such as Lipitor, Niaspan, Zocor, Vytorin, and others;

  
  


• 
  

  gout or arthritis medications (including gold injections);

  
  


• 
  

  HIV/AIDS medication;

  
  


• 
  

  medication for nausea and vomiting, stomach ulcers, or irritable bowel syndrome;

  
  


• 
  

  medicines to treat psychiatric disorders;

  
  


• 
  

  an NSAID such as Advil, Aleve, Arthrotec, Cataflam, Celebrex, Indocin, Motrin, Naprosyn, Treximet, Voltaren, others; or

  
  


• 
  

  seizure medication.

  
  

This list is not complete and there may be other drugs that can affect acetaminophen, chlorpheniramine, and dextromethorphan. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Tylenol Childrens Plus Cough & Runny Nose resources

• Tylenol Childrens Plus Cough & Runny Nose Side Effects (in more detail)
• Tylenol Childrens Plus Cough & Runny Nose Use in Pregnancy & Breastfeeding
• Tylenol Childrens Plus Cough & Runny Nose Drug Interactions
• 0 Reviews for Tylenol Childrens Plus Cough & Runny Nose - Add your own review/rating

Compare Tylenol Childrens Plus Cough & Runny Nose with other medications

• Cold Symptoms
• Influenza

Where can I get more information?

• Your pharmacist can provide more information about acetaminophen, chlorpheniramine, and dextromethorphan.

See also: Tylenol Childrens Plus Cough & Runny Nose side effects (in more detail)

Tricof Syrup

Pronunciation: klor-fen-EER-a-meen/dye-hye-droe-KOE-deen/sue-do-eh-FED-rin
Generic Name: Chlorpheniramine/Dihydrocodeine/Pseudoephedrine
Brand Name: Examples include Pancof and Tricof

Tricof Syrup is used for:

Treating symptoms of the common cold, flu, or hay fever, and other upper respiratory allergies such as cough, congestion, runny nose, sneezing, itching of the nose and throat, and itchy, watery eyes. Tricof Syrup may also be used for other conditions as determined by your doctor.

Tricof Syrup is a narcotic antitussive (cough suppressant), antihistamine, and decongestant combination. The antitussive works by suppressing the cough center in the brain. The antihistamine works by blocking the action of histamine, which reduces the symptoms of an allergic reaction such as itch, watery eyes and runny nose. The decongestant shrinks swollen nasal passages, which relieves nasal congestion.

Do NOT use Tricof Syrup if:

• you are allergic to any ingredient in Tricof Syrup or any other codeine-related medicine (eg, codeine)


• you have diarrhea associated with poisoning, antibiotic use, or a bacterial infection (from eating or drinking contaminated food or water)


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you are taking sodium oxybate (GHB) or if you have taken furazolidone or a monoamine oxidase (MAO) inhibitor (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tricof Syrup:

Some medical conditions may interact with Tricof Syrup. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of alcohol or drug abuse, dependence on narcotics, or suicidal thoughts or behaviors


• if you have increased pressure in the head, an unusual growth in the brain (eg, tumor), a recent head injury, Parkinson disease, Reye syndrome, the blood disease porphyria, or a blockage of your stomach, bowel, or bladder


• if you have a history of epilepsy or seizures, asthma or other breathing problems (eg, sleep apnea), stomach or intestinal problems, chronic constipation, liver problems, glaucoma, an enlarged prostate gland or other prostate problems, difficulty urinating, heart problems, diabetes, high blood pressure, blood vessel problems, adrenal gland problems, overactive thyroid, seizures, or stroke


• if you have recently had abdominal surgery

Some MEDICINES MAY INTERACT with Tricof Syrup. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturate anesthetics (eg, thiopental), beta-blockers (eg, propranolol), cimetidine, catechol-O-methyltransferase (COMT) inhibitors (eg, tolcapone), furazolidone, indomethacin, ketorolac, MAO inhibitors (eg, phenelzine), naltrexone, sodium oxybate (GHB), or tricyclic antidepressants (eg, amitriptyline) because side effects of Tricof Syrup may be increased, including dangerous sleepiness and a decrease in the ability to breathe


• Digoxin or droxidopa because the risk of irregular heartbeat or heart attack may be increased


• Rifampin or risperidone because the effectiveness of Tricof Syrup may be decreased


• Bromocriptine or hydantoins (eg, phenytoin) because the actions and side effects may be increased by Tricof Syrup


• Guanadrel, guanethidine, mecamylamine, methyldopa, mexiletine, or reserpine because the effectiveness may be decreased by Tricof Syrup


• Naltrexone because the effectiveness of Tricof Syrup will be decreased and withdrawal symptoms may occur in patients who have become physically dependent on opioids. You must not take naltrexone until you have stopped taking Tricof Syrup for 7 to 10 days and after a naloxone challenge test is negative.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tricof Syrup may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tricof Syrup:

Use Tricof Syrup as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Tricof Syrup may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Tricof Syrup and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tricof Syrup.

Important safety information:

• Tricof Syrup may cause dizziness or drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Tricof Syrup. Using Tricof Syrup alone, with other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.


• Do not drink alcohol while you are using Tricof Syrup. Avoid taking other medications that cause drowsiness (eg, sedatives, tranquilizers) while taking Tricof Syrup. Tricof Syrup will add to the effects of alcohol and other depressants. Ask your pharmacist if you have questions about which medicines are depressants.


• If your symptoms do not improve within 7 days or if you develop a high fever or persistent headache, check with your doctor.


• Use Tricof Syrup with caution in the ELDERLY because they may be more sensitive to its effects, especially possible breathing problems and drowsiness.


• Use Tricof Syrup with extreme caution in CHILDREN. Safety and effectiveness have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is unknown if Tricof Syrup can cause harm to the fetus. If you become pregnant while taking Tricof Syrup, discuss with your doctor the benefits and risks of using Tricof Syrup during pregnancy. Tricof Syrup is excreted in breast milk. If you are or will be breast-feeding while you are using Tricof Syrup, check with your doctor or pharmacist to discuss the risks to your baby.

Use of Tricof Syrup can lead to TOLERANCE. When using for an extended period, Tricof Syrup may not work as well and may require different dosing. Talk with your doctor if Tricof Syrup stops working well.

Long-term use of Tricof Syrup can lead to physical DEPENDENCE. The early sign of addiction is medicine ineffectiveness. Dependence is not an issue in terminal illness, when pain relief is more important. If using Tricof Syrup for an extended period of time, do not suddenly stop taking Tricof Syrup without your doctor's approval. WITHDRAWAL symptoms have occurred when Tricof Syrup is suddenly stopped and may include anxiety; diarrhea; fever; runny nose or sneezing; goose bumps and abnormal skin sensations; nausea and vomiting; pain; rigid muscles; seeing, hearing, or feeling things that are not there; shivering or tremors; sweating; trouble sleeping. Contact your doctor if you notice any of these symptoms after stopping use of Tricof Syrup.

Possible side effects of Tricof Syrup:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; flushing or redness of face.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Tricof side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; coma; confusion; deep sleep or loss of consciousness; difficulty breathing; diminished mental alertness; hallucinations; hot or cold skin; large and unchanging pupils; sedation; seizures; shaking; sleeplessness; slowed breathing; slow heartbeat.

Proper storage of Tricof Syrup:

Store Tricof Syrup at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tricof Syrup out of the reach of children and away from pets.

General information:

• If you have any questions about Tricof Syrup, please talk with your doctor, pharmacist, or other health care provider.


• Tricof Syrup is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tricof Syrup. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tricof resources

• Tricof Side Effects (in more detail)
• Tricof Use in Pregnancy & Breastfeeding
• Tricof Drug Interactions
• Tricof Support Group
• 0 Reviews for Tricof - Add your own review/rating

Compare Tricof with other medications

• Cough and Nasal Congestion

Tussigon

Pronunciation: hoe-MA-troe-peen/HIGH-droe-KOE-dohn
Generic Name: Homatropine/Hydrocodone
Brand Name: Tussigon

Tussigon is used for:

Temporary relief of cough. It may also be used for other conditions as determined by your doctor.

Tussigon is an anticholinergic and narcotic cough suppressant combination. The anticholinergic works by drying up secretions and the narcotic depresses the cough reflex in the brain.

Do NOT use Tussigon if:

• you are allergic to any ingredient in Tussigon or any morphine-related medicine (eg, codeine, oxycodone)


• you have diarrhea due to food poisoning or pseudomembranous colitis


• you are taking sodium oxybate (GHB)

Contact your doctor or health care provider right away if any of these apply to you.

Before using Tussigon:

Some medical conditions may interact with Tussigon. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine (including any cough-and-cold products or medicines that cause drowsiness), herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have arteriosclerosis (hardening of the arteries) or other heart problems (eg, congestive heart failure)


• if you have high blood pressure, thyroid problems, stomach problems (eg, surgery, severe inflammatory bowel disease, chronic constipation, obstruction), or liver disease


• if you use alcohol or are dependent on drugs


• if you have lung disease (eg, asthma, history of severe breathing problems), a seizure disorder, serious head injury or brain disease, psychiatric problems (eg, suicidal thoughts), glaucoma, or sleep apnea

Some MEDICINES MAY INTERACT with Tussigon. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Barbiturate anesthetics (eg, thiopental), cimetidine, monoamine oxidase inhibitors (MAOIs) (eg, phenelzine), narcotic pain medicines (eg, codeine), and sodium oxybate (GHB) because they may increase the risk of Tussigon's side effects


• Naltrexone because it may decrease Tussigon's effectiveness

This may not be a complete list of all interactions that may occur. Ask your health care provider if Tussigon may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Tussigon:

Use Tussigon as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Tussigon by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• If you miss a dose of Tussigon and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Tussigon.

Important safety information:

• Tussigon may cause dizziness, drowsiness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Tussigon with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• If your symptoms do not get better within 7 days or if you develop a high fever or persistent headache, check with your doctor.


• Tussigon may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Tussigon.


• Use Tussigon with caution in the ELDERLY; they may be more sensitive to its effects.


• Tussigon should be used with extreme caution in CHILDREN younger than 6 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: It is not known if Tussigon can cause harm to the fetus. If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Tussigon while you are pregnant. It is not known if Tussigon is found in breast milk. Do not breast-feed while taking Tussigon.

Some people who use Tussigon for a long time may develop a need to continue taking it. People who take high doses are also at risk. This is known as DEPENDENCE or addiction. If you stop taking Tussigon suddenly, you may have WITHDRAWAL symptoms. These may include feeling unwell or unhappy, anxious or irritable, dizzy, confused, or agitated. You may also have nausea, unusual skin sensations, mood swings, headache, trouble sleeping, or sweating. If you need to stop Tussigon, your doctor will lower your dose over time.

Possible side effects of Tussigon:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Blurred vision; constipation; dizziness; drowsiness; dry mouth, throat, or nose; excitement; nausea; stomach upset; thickening or mucus in nose or throat.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; flushing; rapid or pounding heartbeat; redness of face; severe drowsiness or dizziness.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Tussigon side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include agitation; coma; confusion; deep sleep or loss of consciousness; difficulty breathing; diminished mental alertness; hallucinations; hot or cold skin; large and unchanging pupils; sedation; seizures; shaking; sleeplessness; slow heartbeat; slowed breathing.

Proper storage of Tussigon:

Store Tussigon at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Tussigon out of the reach of children and away from pets.

General information:

• If you have any questions about Tussigon, please talk with your doctor, pharmacist, or other health care provider.


• Tussigon is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Tussigon. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Tussigon resources

• Tussigon Side Effects (in more detail)
• Tussigon Dosage
• Tussigon Use in Pregnancy & Breastfeeding
• Tussigon Drug Interactions
• Tussigon Support Group
• 1 Review for Tussigon - Add your own review/rating

• Tussigon Concise Consumer Information (Cerner Multum)


• Tussigon Prescribing Information (FDA)


• Hycodan Prescribing Information (FDA)


• Hydromet Prescribing Information (FDA)

Compare Tussigon with other medications

• Cough

trifluridine ophthalmic

Generic Name: trifluridine ophthalmic (trye FLURE i deen off THAL mik)

Brand Names: Trifluridine, Viroptic

What is trifluridine ophthalmic?

Trifluridine ophthalmic is an antiviral medication. It fights eye infections that are caused by certain viruses.

Trifluridine ophthalmic is used to treat eye infections caused by the herpes simplex virus, which can lead to swelling or ulcers in the eyelids or cornea (surface of the eyeball).

Trifluridine ophthalmic may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about trifluridine ophthalmic?

Do not use this medication if you are allergic to trifluridine. This medication will not treat an infection that is caused by bacteria or fungus.

The usual dose of trifluridine ophthalmic is one drop into the affected eye every 2 hours while you are awake. Do not use more than 9 drops in the course of one full day.

Once your condition improves, you may need to keep using the medication 4 times daily (up to 5 drops per day) for another 7 days. Your doctor should check your eyes to determine how long you need to use the medicine.

If you wear contact lenses, remove them before applying trifluridine ophthalmic. Ask your doctor if contact lenses can be reinserted after putting in the eye drops.

Avoid using other eye medications while using trifluridine ophthalmic, unless your doctor has told you to.

Trifluridine ophthalmic may cause blurred vision. Be careful if you drive, operate machinery, or do anything else that requires you to be able to see clearly.

Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

Do not use the eye drops if the liquid has changed colors or has particles in it.

Contact your doctor if your symptoms do not improve, or if they get worse after using this medication for 7 days.

What should I discuss with my healthcare provider before using trifluridine ophthalmic?

Do not use this medication if you are allergic to trifluridine. This medication will not treat an infection that is caused by bacteria or fungus. FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. It is not known whether trifluridine ophthalmic passes into breast milk or if it could harm a nursing baby. Do not use this medication without telling your doctor if you are breast-feeding a baby. Do not use this medication in a child younger than 6 years old.

How should I use trifluridine ophthalmic?

Use this medication exactly as it was prescribed for you. Do not use the medication in larger amounts, or use it for longer than recommended by your doctor. Follow the instructions on your prescription label.

The usual dose of trifluridine ophthalmic is one drop into the affected eye every 2 hours while you are awake. Do not use more than 9 drops in the course of one full day.

Once your condition improves, you may need to keep using the medication 4 times daily (up to 5 drops per day) for another 7 days. Your doctor should check your eyes to determine how long you need to use the medicine.

Wash your hands before using the eye drops.

If you wear contact lenses, remove them before applying trifluridine ophthalmic. Ask your doctor if contact lenses can be reinserted after putting in the eye drops.

To apply the eye drops:

• 
  

  Tilt your head back slightly and pull down your lower eyelid. Hold the dropper above the eye with the dropper tip down. Look up and away from the dropper as you squeeze out a drop, then close your eye. Gently press your finger to the inside corner of the eye (near your nose) for about 1 minute to keep the liquid from draining into your tear duct.

  
  


• 
  

  Do not allow the dropper tip to touch any surface, including the eyes or hands. If the dropper becomes contaminated it could cause an infection in your eye, which can lead to vision loss or serious damage to the eye.

  
  

Do not use the eye drops if the liquid has changed colors or has particles in it.

Contact your doctor if your symptoms do not improve, or if they get worse after using this medication for 7 days.

Store the eye drops at room temperature away from heat and moisture. Keep the bottle tightly closed when not in use.

What happens if I miss a dose?

Use the medication as soon as you remember the missed dose. If it is almost time for your next dose, skip the missed dose and use the medicine at your next regularly scheduled time. Do not use extra medicine to make up the missed dose.

What happens if I overdose?

Rinse the eye with water and seek emergency medical attention if you think you have used too much of this medicine.

An overdose of trifluridine ophthalmic is not expected to produce life-threatening symptoms.

What should I avoid while taking trifluridine ophthalmic?

This medication may cause blurred vision. Be careful if you drive, operate machinery, or do anything else that requires you to be able to see clearly.

Avoid using other eye medications while using trifluridine ophthalmic, unless your doctor has told you to.

Trifluridine ophthalmic side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using trifluridine ophthalmic and call your doctor at once if you have any of these serious side effects:

• 
  

  severe swelling around your eyes;

  
  


• 
  

  tunnel vision; or

  
  


• 
  

  severe pain, burning, or other irritation of your eyes.

  
  

Keep using the medication and talk to your doctor if you have any of these less serious side effects:

• 
  

  mild eye pain, burning, stinging, itching, or redness;

  
  


• 
  

  blurred vision; or

  
  


• 
  

  feeling of pressure inside the eye.

  
  

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect trifluridine ophthalmic?

There may be other drugs that can affect trifluridine ophthalmic. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More trifluridine ophthalmic resources

• Trifluridine ophthalmic Side Effects (in more detail)
• Trifluridine ophthalmic Use in Pregnancy & Breastfeeding
• Trifluridine ophthalmic Support Group
• 0 Reviews for Trifluridine - Add your own review/rating

• Viroptic Prescribing Information (FDA)


• Viroptic Monograph (AHFS DI)


• Viroptic Advanced Consumer (Micromedex) - Includes Dosage Information


• Viroptic Drops MedFacts Consumer Leaflet (Wolters Kluwer)

Compare trifluridine ophthalmic with other medications

• Herpetic Keratitis

Where can I get more information?

• Your pharmacist has information about trifluridine ophthalmic written for health professionals that you may read.

See also: trifluridine side effects (in more detail)